Cilostazol - reversibly oppresses aggregation of thrombocytes caused by various incentives, surpassing in this respect Аspirin, Dipiridamolum, Тiclopidine and Pentoxifylline. It also inhibits formation of arterial blood clots and proliferation of smooth muscle cells, possesses vasodilating action.
Cilostazol
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 100mg × 30 Pills | $1.80 | $53.94 + Bonus - 4 Pills | - | Add to cart |
| 100mg × 60 Pills | $1.46 | $87.64 + Bonus - 4 Pills | $20.40 | Add to cart |
| 100mg × 90 Pills | $1.35 | $121.36 + Bonus - 7 Pills | $40.50 | Add to cart |
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Cilostazol product description
Cilostazol is an antiplatelet drug that increases intracellular cAMP content in platelets, selectively inhibits type 3 phosphodiesterase, thereby lessens the platelet aggregate ability. According to experimental data, cilostazol suppresses the synthesis of DNA and inhibits the growth of smooth muscle cells, in addition, it has a vasodilating action. These properties of cilostazol allowed us to advise it for the prevention of restenosis after implantation of metallic uncoated stents. Cilostazol is consumed to eliminate the functional limitations of the limbs that arise from cramping pains with the insufficient circulation. So, in case of the Charcot syndrome, this medical remedy allows patients to walk much longer without feeling much discomfort.
Cilostazol safety information
This pharmaceutical product should be taken on an empty stomach, at least 30 minutes before or two hours after a meal. The maximum effect of the remedy may appear only after 12 weeks of its proper reception, although often the signs of the successful healing with the medicine are palpable earlier. Immediately stop taking this medical remedy if bleeding occurs from the eyes. Also, you should seek an advice if you have got bruises during the therapy. If the patient needs to undergo surgery, then the drug should be withdrawn 5 days before the surgery. If it is administered in parallel with the other chemicals, which are thinning the blood or lowering blood pressure, as well as with inhibitors or inducers of CYP 3A4, CYP 2C19 or CYP 3A4 substrates, it is necessary to exercise extra caution. If during therapy, the patient has a sore throat or hyperthermia, a laboratory test should be carried out for pathological changes. In case of such changes, the medical care with Cilostazol should be discontinued immediately.
Contraindications
If the patient underwent a surgery on coronary vessels in the last half of the year, then Cilostazol should be assigned.
Cilostazol is not received if the patient has detected to have any of the following condition: hypersensitivity to the basic substance or to any component of this pharmaceutical product, any known tendency to bleeding (eg, gastric or duodenal ulcer in the acute stage, recent hemorrhagic stroke), congestive heart failure, moderate or severe hepatic insufficiency , severe renal failure.
The very medical preparation is not prescribed for the therapy of pregnant women and children since there are no data on studies of possible negative consequences.
Cilostazol side effects
From the side of the nervous system: a headache, dizziness.
From the side of the cardiovascular system: palpitation, tachycardia, angina pectoris, arrhythmia, ventricular extrasystoles.
On the part of the respiratory tract: rhinitis, pharyngitis.
On the part of the gastrointestinal tract: diarrhea, nausea, vomiting, dyspepsia, flatulence, abdominal pain, impaired excrement.
On the part of the skin: rash, itching.
Common disorders: chest pain, bruises, asthenia.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
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The medicine is a cardioselective blocker of beta-1-adrenergic receptors. A major risk index for glaucomatous scotoma is an increased tension. When its rate is soaring, the eyes are more damaged. As a consequence, a visual field narrows. Betoptic reduces both increased and usual pressure, regardless of if it occurs with glaucoma, or not; the structure of its activity is connected with a decline in the performance of intraocular fluid. Betaxolol acts after half-an-hour, and the expected result is normally achieved after 2 hours after application.
Coumadin is a drug that promotes blood thinning in the veins. Within a short period of application, anticoagulant reduces viscous blood consistency and lowers the risk of blood clots. The drug is prescribed only after laboratory blood tests when certain symptoms are detected. Independent use of tablets is prohibited, only a doctor may establish the need for taking the drug. Thrombosis is a disease that is characterized by the formation of blood clots. In case of delayed treatment, this disease may cause disorders of oxygen metabolism in the blood and embolism.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
