Xenical - a powerful, specific and reversible inhibitor of gastrointestinal lipases, which has a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine portion of the gastric and pancreatic lipases. The inactivated enzyme at the same time loses the ability to break down food fats coming in the form of triglycerides, to sucking free fatty acids and monoglycerides. Since uncleaved triglycerides are not absorbed, the resulting decrease in the intake of calories into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.
Xenical
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 120mg × 30 Pills | $2.20 | $65.98 + Bonus - 4 Pills | - | Add to cart |
| 120mg × 60 Pills | $1.77 | $105.98 + Bonus - 4 Pills | $25.80 | Add to cart |
| 120mg × 90 Pills | $1.62 | $145.99 + Bonus - 7 Pills | $52.20 | Add to cart |
| 120mg × 120 Pills | $1.55 | $185.99 + Bonus - 7 Pills | $78.00 | Add to cart |
| 120mg × 180 Pills | $1.48 | $265.99 + Bonus - 11 Pills Free Trackable Delivery | $129.60 | Add to cart |
| 120mg × 270 Pills | $1.43 | $385.99 + Bonus - 11 Pills Free Trackable Delivery | $207.90 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 60mg × 30 Pills | $1.39 | $41.76 + Bonus - 4 Pills | - | Add to cart |
| 60mg × 60 Pills | $1.10 | $66.14 + Bonus - 4 Pills | $17.40 | Add to cart |
| 60mg × 90 Pills | $1.01 | $90.52 + Bonus - 7 Pills | $34.20 | Add to cart |
| 60mg × 120 Pills | $0.96 | $114.89 + Bonus - 7 Pills | $51.60 | Add to cart |
| 60mg × 180 Pills | $0.91 | $163.66 + Bonus - 11 Pills | $86.40 | Add to cart |
| 60mg × 270 Pills | $0.88 | $236.79 + Bonus - 11 Pills Free Trackable Delivery | $137.70 | Add to cart |
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Xenical product description
Drug uses
Xenical is a gastrointestinal lipase inhibitor, used to treat obesity and overweight in patients with BMI* ≥ 30 kg/m2 or BMI ≥ 27 kg/m2 with associated risk factors (excess visceral fat, hypertension, diabetes).
Xenical can also be used for reducing the risk of weight regain in obese patients after prior weight loss. Xenical is recommended in combination with a reduced-calorie diet and physical exercise in adults and adolescents aged 12 years or older.
Xenical benefit comparing to other anti-obesity drugs is that this medication is not actually absorbed from the digestive tract and does not enter the systemic blood. Therefore, Xenical is well tolerated and does not cause any serious side effects in patients.
The recommended dose of Xenical is 120mg three times a day during a main meal or within one hour after it.
* BMI is defined as the body mass divided by the square of the body height.
Missed dose
During the treatment of obesity with Xenical, a missed dose does not have a serious negative effect on the therapy of excess weight. Yet, the patients are advised not to miss the therapeutic dose of the drug and to take it according to the scheduled dosing regimen.
If the patient has forgotten to take Xenical on time, he/she should skip the missed dose and wait for the next food intake. Do not double the dose of Xenical to make up for a missed dose, as it may cause side effects.
More information
The daily dose of Xenical is not recommended to be increased (more than 360mg), because it does not increase the therapeutic effect.
The probability of adverse reactions from the gastrointestinal tract can be increased if the patient is taking Xenical with high-fat foods. Therefore, the patient is recommended to control caloric intake to reduce any risk of adverse effects.
In patients with type 2 diabetes, a dose of hypoglycemic agents (for example, sulfonylureas) can be required to be decreased.
Storage
It is recommended to keep Xenical in an original container or package in order to protect capsules from moisture and light. Store Xenical capsules at room temperature below 30°C and out of the reach of children.
Xenical safety information
Warnings
Patients taking antiepileptic drugs should be careful, because their simultaneous use with Xenical may develop seizures. Xenical prevents absorption of some fat-soluble vitamins, consumed with the food, so the patients are advised to take additional multivitamin complex. Vitamins are recommended to be taken two hours before or after Xenical.
Disclaimer
The online pharmacy publish this review of Xenical to provide consumers with information about obesity for informational purposes only, and the review is not intended to supplant the guidance or advice of the primary health care worker. In no event will the online pharmacy be liable for any damage, harm or loss, arising out of or in connection with the use of this information about anti-obesity agent Xenical.
Xenical side effects
Usually Xenical may cause gastrointestinal adverse events that normally pass mildly during long-term therapy with this anti-obesity agent. Adverse events are rarely reported to cease the use of Xenical. Generally, the adverse events during therapy with the anti-obesity agent are associated with a high level of fat consumed with food.
The most common adverse events caused by Xenical include flatulence, oily or liquid stool, oily spotting from the rectum, abdominal pain, oily evacuation, hypoglycemia, URI, influenza, or headache. Xenical may also cause abdominal distension, or hypoglycemia in patients with diabetes.
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Baycip - the drug, which is highly effective at infections of urinary tracts; at intake it quickly gets into kidneys, has a long-term effuse, has bactericidal effect on Pseudomonasaeruginosa. Drug is prescribed at treatment of oncological patients. It is prescribed when it is diagnosed different respiratory infections, of skin and soft tissues, bones and joints, digestive tract, including the infections caused by a salmonella, a shigella, campylobacters.
Claritin prevents development and facilitates the course of allergic reactions. Possesses antiallergic, antipruritic, antiexudative action. Reduces permeability of capillaries, controls oedemata of tissues, removes spasms of smooth muscles. It is prescribed at allergic rhinitis, conjunctivitis, pollinosis, urticaria fever, angioedema, pruritic dermatosis; pseudo-allergic reactions, caused by release of histamine; allergic reactions at stings of insects.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
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