Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.
Imuran
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Imuran Product Description
Drug Uses
Imuran is an immunosuppressive agent used for the suppression of immune responses in the treatment of autoimmune diseases or after organ transplantation. Imuran tablets can be used alone, or as a part of combined immunomodulatory therapy.
As an immunosuppressive antimetabolite, Imuran is approved as:
- Prevention of rejection of transplanted organs and improved survival after organ transplantation (including for medical management of renal, cardiac and hepatic transplant recipients).
- Management of active, severe, inflammatory and chronic autoimmune diseases of joints, skin, skeletal muscles, blood cells, arteries, liver and other organs and body systems.
Imuran maintenance dose to prevent transplant rejection ranges from 1mg to 4mg (once a day). The maintenance daily doses of Imuran for patients with autoimmune diseases vary from 1mg to 3mg (as a single or two divided doses).
Missed dose
If you take Imuran several times a day and skip a regular dose, take it as soon as you remember. Do not double Imuran dose and do not take extra immunosuppressive drugs to make up the missed dose.
More Information
To prevent transplant rejection, Imuran can be used together with other immunosuppressive agents. For symptomatic treatment of autoimmune diseases, Imuran can be used together with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs).
Storage
Imuran tablets should be protected from direct sunlight and stored in a dry place, at room temperature not exceeding 30°C.
Imuran Safety Information
Warnings
Drugs suppressing immune responses (such as, Imuran) may increase the risk of developing malignancies. Patients with high risk of malignancies should be prescribed with Imuran only if the benefits of immunosuppressive therapy outweigh the potential risks.
Disclaimer
Data about immunosuppressive therapy represented in this Imuran review is intended only for general information. This information in no case does not constitute an offer of a substitute for the immunologist’s professional medical advice or diagnosis of immune diseases. The online pharmacy shall not be held responsible for any damages resulting from the use of information about transplantation, autoimmune diseases and Imuran.
Imuran Side Effects
Imuran adverse reactions are reversible and disappear when decreasing the dose or duration of immunosuppressive therapy. The most severe adverse reactions of Imuran are hematologic and gastrointestinal disorders, such as leucopenia, infection, anemia, nausea, vomiting, hepatic toxicity, diarrhea, fever, malaise, vasculitis or muscle pain. Less often, Imuran may cause skin rashes, hair loss, fever, joint pain, steatorrhea, infections (e.g. viral, fungal and bacterial) or exanthem.
Furosemide - «Loopback" diuretic; causes quickly coming, severe and short-term diuresis. Has natriuretic and chloro effects, increases clearance of K+, Ca2+, Mg2+. It is taken at edematous syndrome, cirrhosis, diseases of kidneys, heavy course of arterial hypertension and hypercalcemia.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
Prograf The active ingredient of the drug (Tacrolimus) binds to cytosolic protein (FKBP12), responsible for the intracellular accumulation of the drug. Designed for the prevention and treatment of allograft liver, kidneys and heart rejection reactions, including those resistant to standard immunosuppressive therapy regimes.
Amaryl - a medicine of group of sulphonylurea, the peroral hypoglycemic medicine. It has an initially prolonged effect. The mechanism of action consists in stimulation of secretion and release of insulin from beta cells of a pancreas (pancreatic effect). It also increases sensitivity of fatty and muscular tissues to effect of insulin (extrapancreatic effect).
Antidepressant; a specific inhibitor of serotonin reuptake by neurons of the brain. Has no stimulating or sedative effect, does not affect choline, muscarin-, histamine- and adrenergic processes. The therapeutic effect develops 1-4 weeks after the initiation of therapy.
An antidepressant used in cases of deep depression, panic disorders, social anxiety disorders, anxiety disorders. The mechanism of its action is based on the ability to selectively block the reuptake of serotonin by the presynaptic membrane of the neurons of the brain. Consequently, its serotonergic effect in the central nervous system that is responsible for the development of antidepressant effect, increases, which determines the effectiveness in the treatment of panic and social anxiety disorder.
It is a nonsteroidal anti-inflammatory agent that effectively inhibits the synthesis of prostaglandins, has antipyretic, anti-inflammatory and analgesic effects. In addition, it reversibly inhibits collagen-induced platelet aggregation. In oral administration, the drug is partly absorbed in the abdomen and then completely in the intestine. After metabolism in the liver (hydroxylation, carboxylation) pharmacologically inactive metabolites are completely excreted in the urine. In oral administration, the maximum concentration in blood plasma is achieved in 1-2 hours.
Fildena is the drug which the main component is Sildenafil Citrate. Sildenafil Citrate was invented for cough treatment but it helped to maintain an erection. That’s how the Viagra was invented. Its invention gave a start to other Sildenafil Citrate analog’s inventions like Fildena. It’s an effective medicine that copes with men’s impotence, premature ejaculation, and diminishes an enlarged prostate. Erectile dysfunction is the result of health problems, exhaustion, bad habits, drug dependence, alcohol abuse, and traumas. Fildena is one of the possible variants of ED treatment.
Vasotec- an antihypertensive drug based on the action of the active ingredient Enalapril, whose mechanism of action is associated with inhibition of the activity of the angiotensin-converting enzyme, leading to a decrease in the formation of the vasoconstrictor factor - angiotensin II and simultaneously to the activation of the formation of kinin and prostacyclin possessing a vasodilating action.
Peripheral vasodilator with predominant effect on venous vessels. It is used for the prevention of angina in CHF, hypertension in the "small" circulation, "pulmonary" heart (treatment as a part of combination therapy), spasm of peripheral arteries (obliterating endarteritis, angiospastic retinitis)
Artane, which is trihexyphenidyl - has a prominent central and peripheral cholinolytic effect. It is prescribed to patients with the diagnosed Parkinsonism of various etiology and other diseases of extrapyramidal system which are followed by increase in a muscle tone and hyperkinesias (violent automatic movements owing to involuntary reduction of muscles).
Doryx MPC (doxycycline hyclate) delayed-release tablets for oral use, contain doxycycline hyclate, a tetracycline class drug synthetically derived from oxytetracycline, in a delayed-release formulation consisting of pellets with a modified polymer enteric coat that has increased acid resistance.
Calcort is a steroid that reduces inflammation in the body.
Calcort is used to treat Duchenne muscular dystrophy in adults and children who are at least 5 years old.
Calcort is not a cure for muscular dystrophy, but this medicine may improve muscle strength and slow the progression of disability.
Calcort may also be used for purposes not listed in this medication guide.