Bystolic is an anti-anginal, antihypertensive anti-arrhythmic drug. It stimulates the internal surface of the blood vessels (endothelium) for the production of nitric oxide, which also helps the vessels to relax. It is used for hypertension, IHD, Stenocardia tension.
Bystolic
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 10mg × 30 Pills | $3.29 | $98.77 + Bonus - 4 Pills | - | Add to cart |
| 10mg × 60 Pills | $3.10 | $185.71 + Bonus - 4 Pills | $11.40 | Add to cart |
| 10mg × 120 Pills | $3.00 | $359.59 + Bonus - 7 Pills Free Trackable Delivery | $34.80 | Add to cart |
| 10mg × 240 Pills | $2.95 | $707.35 + Bonus - 11 Pills Free Trackable Delivery | $81.60 | Add to cart |
| 10mg × 300 Pills | $2.94 | $881.23 + Bonus - 11 Pills Free Trackable Delivery | $105.00 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 5mg × 30 Pills | $1.70 | $50.86 + Bonus - 4 Pills | - | Add to cart |
| 5mg × 60 Pills | $1.37 | $82.26 + Bonus - 4 Pills | $19.80 | Add to cart |
| 5mg × 90 Pills | $1.26 | $113.67 + Bonus - 7 Pills | $39.60 | Add to cart |
| 5mg × 120 Pills | $1.21 | $145.08 + Bonus - 7 Pills | $58.80 | Add to cart |
| 5mg × 180 Pills | $1.15 | $207.89 + Bonus - 11 Pills Free Trackable Delivery | $99.00 | Add to cart |
| 5mg × 270 Pills | $1.12 | $302.10 + Bonus - 11 Pills Free Trackable Delivery | $156.60 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 2.5mg × 30 Pills | $1.35 | $40.64 + Bonus - 4 Pills | - | Add to cart |
| 2.5mg × 60 Pills | $1.10 | $65.93 + Bonus - 4 Pills | $15.00 | Add to cart |
| 2.5mg × 120 Pills | $0.97 | $116.53 + Bonus - 7 Pills | $45.60 | Add to cart |
| 2.5mg × 240 Pills | $0.91 | $217.74 + Bonus - 11 Pills Free Trackable Delivery | $105.60 | Add to cart |
| 2.5mg × 300 Pills | $0.89 | $268.34 + Bonus - 11 Pills Free Trackable Delivery | $138.00 | Add to cart |
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Product Description
Bystolic helps to reduce heart rate, reduces arterial pressure at rest and during exercising regardless the initial level of arterial pressure. With prolonged therapy, the hypotensive effect of Bistolic does not change.
Safety information
Indications
Bystolic is used to treat patients with an essential form of hypertension. Bystolic can be prescribed in a complex therapy of elderly patients with stable chronic heart failure of moderate severity.
Directions
Bystolic is taken orally. Bystolic pills can be taken regarless of food intake regime. It is recommended to take the drug at the same time of a day. As a rule, the daily dose of Bystolic is prescribed for single take. The duration of therapy as well as the dosage of Bystolic is determined by doctor. Adults with an essential form of arterial hypertension are usually recommended to take 5mg of Bystolic a day. If in four weeks after the beginning of therapy with Bystolic, the arterial pressure control is insufficient, additional therapy is prescribed including the recommended combination of Bystolic in a standard daily dose with hydrochlorothiazide in a daily dose of 12.5-25mg. If there’s a need of cancelling Bystolic treatment, the dose is recommended to be reduced gradually as the abrupt cancellation can lead to a temporary increase in the symptoms of heart failure.
Contraindications
Bystolic is not used for the treatment in patients with intolerance to the active ingredient of the drug, glucose-galactose absorption disorder, lactase deficiency, and galactoseemia; hepatic dysfunction, cardiogenic shock, sinus node weakness syndrome, second- and third-degree atrioventricular blockade without an artificial sinoatrial node, compensated heart failure.
Bystolic is not used to treat patients with bronchial asthma and with a tendency of bronchospasm development, untreated pheochromocytoma, metabolic acidosis, bradycardia, arterial hypotension, as well as severe peripheral blood flow disorders, congestive heart failure, peripheral circulatory disorders, atrioventricular blockade of the first degree, and Prinzmetal’s angina
Side effects
As a rule, Bystolic is well tolerated by patients. However, Bystolic may cause the possibility of developing such undesirable effects as: depressive conditions, nightmares, headache, paresthesia, dizziness, asthenia, syncope, decreased visual acuity. In addition, in isolated cases, there was a development of hallucinations, psychosis and loss of consciousness, bradycardia, heart failure, atrioventricular conduction disorders, excessive blood pressure lowering, exacerbation of intermittent claudication, dyspepsia, vomiting, nausea, stool disorders, flatulence, bronchospasm, Quincke's edema, Erythema, urticaria, exacerbation of psoriasis, increased fatigue, impotence, swelling, dry eye, mucous cyanosis of the extremities.
For patients who use contact lenses, in case of eye mucosa dryness developing, it is recommended to use artificial tears or wear glasses during Bystolic therapy.
Vastarel - the main substance of the drug is trimetazidine, which is used for the prevention of angina attacks in IHD, as well as in vertigo caused by violations of cerebral circulation, Meniere's disease, noise in the ears. It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly associated with its antioxidant and antihypoxic properties and cytoprotective effects on the function of cardiomyocytes.
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Peripheral vasodilator with predominant effect on venous vessels. Reduces the need for myocardium in oxygen by reducing preload and afterload (reduces the end diastolic volume of the LV and reduces the systolic tension of its walls). Has the coronary dilatation effect. Reduces blood flow to the right atrium, helps to reduce pressure in the "small" circle of blood circulation and regression of symptoms with pulmonary edema. Promotes redistribution of coronary blood flow in the area with reduced blood circulation. Increases tolerance to physical activity in patients with IHD, angina pectoris.
